CRC 969 Seminars

A core issue of the CRC 969 are university-wide seminars dedicated to the presentation and discussion of high-profile research data from expert scientists in the field of proteostasis.

Summer term 2022

Time: Tuesdays, 15:15 h

Location: Room A704

19 April 2022

Neural Network Methods in DEER and RIDME Spectroscopy of Spin-Labelled Proteins

Prof. Ilya Kuprov, University of Southampton

17 May 2022 The Conformational Equilibrium of the Neuropeptide Y2 G-Protein Coupled Receptor in Membranes

Prof. Daniel Huster, University of Leipzig

31 May 2022 Interrogating Transmembrane Signaling by Advanced Light Microscopy

Prof. Jacob Piehler, University of Osnabrück

28 June 2022 Targeted Protein Degradation to Disrupt Gene Control in Cancer

Dr. Georg Winter, CeMM, Vienna

05 July 2022 Assembly and Aggregation – How to Unravel Control Mechanisms with Mass Spectrometry

Prof. Nina Morgner, University of Frankfurt

12 July 2022 Development of a Tool Box of Chemical Probes for Selective Protein Degradation

Prof. Stefan Knapp, University of Frankfurt

         

Winter term 2021/2022: We resume our seminar talks on campus!

Time: Tuesdays, 15:15 h

Location: Room A704

Note that all participants have to stick to the 2G-rule of the University: it is vital that you are either vaccinated or recovered! Please keep the maximal possible distance in the lecture hall and wear a medical face mask. If you have typical corona symptoms such as high temperature and/or cough you are not allowed to enter the University!

30 November 2021

 

Impact of Division History on Neural Stem Cells

Dr. Annina Denoth-Lippuner, University of Zurich

18 January 2022

 

POSTPONED! Mechanisms of Folding and Assembly of Newly Synthesized Proteins

Prof. Bernd Bukau, University of Heidelberg

01 February 2022

 

POSTPONED! Chlamydia – Host Cell Interactions at the Crossroad of Metabolism and Immune Defence

Prof. Thomas Rudel, University of Würzburg

08 February 2022

 

POSTPONED! The Modular Proteome and Its Biological Significance

Prof. Ruedi Aebersold, ETH Zurich

Summer term 2021: Due to the Corona pandemic, all seminars of this term will be given online via Zoom Sessions

Please see also the Data Protection Information

Time: Tuesdays, 15:15 h

01 June 2021

 

Parkin is the First E3 Ligase for the Ubiquitin-Like Modifier FAT10, which Inhibits Parkin Activation and Mitophagy

Dr. Nicola Roverato, University of Konstanz

15 June 2021

 

Deubiquitylases: Druggable Regulators of Protein and Organelle Homeostasis

Prof. Sylvie Urbé, University of Liverpool

13 July 2020

 

Activity-Based Probes as Chemical Tools for Targeting Proteases

Prof. Thomas Böttcher, University of Vienna

20 July 2021

 

Exploring the WW Domain as a Model System for the Design of Miniaturized Proteins

Prof. Franziska Thomas, University of Heidelberg

Winter term 2020/2021: Due to the Corona pandemic, there will be no seminars in this term!

Summer term 2020: Due to the Corona pandemic, all seminars of this term will be postponed!

Time: Tuesdays, 15:15 h

Location: Room A704

Get together: Before the talks, 14:55 h

21 April 2020

 

POSTPONED! The Modular Proteome and Its Biological Significance POSTPONED!

Prof. Ruedi Aebersold, ETH Zürich

23 June 2020

 

POSTPONED! Deubiquitylases: Druggable Regulators of Protein and Organelle Homeostasis POSTPONED!

Prof. Sylvie Urbé, University of Liverpool

30 June 2020

 

POSTPONED! Proteolytic Control of Mitochondrial Plasticity POSTPONED!

Prof. Thomas Langer, University of Köln

14 July 2020

 

POSTPONED! Discovery of Novel sGC Stimulators Riociguat and Vericiguat POSTPONED!

Prof. Joachim Mittendorf, Bayer AG

Winter term 2019/2020

Time: Tuesdays, 15:15 h

Location: Room A704

Get together: Before the talks, 14:55 h

22 October 2019

 

Chemical Physiology of Antibody Conjugates and Natural Products

Dr. Gonçalo Bernardes, University of Cambridge

26 November 2019

 

Macromolecular Phase Separation in Germ Cell Fate

Dr. Shambaditya Saha, IMBA Wien

03 December 2019

 

Cycling to Death: Separase-Triggered Apoptosis by Cleavage of Bcl2 Proteins Enforces Minimal Length of Mitosis

Prof. Olaf Stemmann, University of Bayreuth

10 December 2019

 

Visualization of Ribosomal Subunit Precursors using Cryo-Electron Microscopy – Mechanistic and Evolutionary Insights

Dr. Rainer Nikolay, Charité Berlin

Summer term 2019

Time: Tuesdays, 15:15 h

Location: Room A704

Get together: Before the talks, 14:55 h

07 May 2019

 

Protein Dynamics from Integrative NMR Research

Prof. Dr. Magnus Wolf-Watz, Umeå University

21 May 2019

 

A Beta Barrel for Oil Transport Through Lipid Membranes: Dynamic NMR Structures of AlkL

Dr. Loren Andreas, MPI Göttingen

04 June 2019

 

Ultrahigh-Throughput Evolution and Characterization of RNA Using Droplet-Based Microfluidics

Dr. Michael Ryckelynck, University of Strasbourg

09 July 2019

 

Expanding The Genetic Code – Protein Chemistry in Living Systems

Prof. Dr. Kathrin Lang, TU Munich

Winter term 2018/2019

Time: Tuesdays, 15:15 h

Location: Room A704

Get together: Before the talks, 14:55 h

06 November 2018

 

Different Mitochondrial Unfolded Protein Response Axes to Safeguard Mitochondria

Prof. Dr. Christian Münch, University of Frankfurt

27 November 2018

 

How Bacterial Lipoproteins Influence our Immune System

Prof. Dr. Fritz Götz, University of Tübingen

POSTPONED!!

04 December 2018

From its Evolutionary Origin to the Structure of the Metabolic Network of the Eukaryotic Cell

Prof. Dr. Markus Ralser, Charité Berlin

11 December 2018

 

Killing Cells In and Out of Mitosis

Prof. Dr. Andreas Villunger, Medical University Innsbruck

18 December 2018

 

Activity-Based Profiling of Ubiquitin E3 Ligases: From Parkin to the Impalpable

Dr. Satpal Virdee,  University of Dundee

Summer term 2018

Time: Tuesdays, 15:15 h

Location: Room A704

Get together: Before the talks, 14:55 h

17 April 2018

 

Cats but not Rats? Hominids but not Hamsters?

A Study into the Molecular Mechanism of Type 2 Diabetes Using 2D IR Spectroscopy

Prof. Dr. Martin Zanni, University of Wisconsin, Madison

08 May 2018

 

Programmable Receptors and Reagents for Chromatin Chemical Biology

Prof. Dr. Daniel Summerer, University of Dortmund

29 May 2018

 

Chaperone Control of Neurotoxic Protein Aggregation

Prof. Dr. Stefan Rüdiger, University of Utrecht

05 June 2018

 

In vitro Cross-Reactivity of Parkinson’s Disease Protein, Alpha-Synuclein: Consequences for Amyloid Formation

Prof. Dr. Pernilla Wittung-Stafshede, Chalmers University Gothenburg

Winter term 2017/2018

Time: Tuesdays, 15:15 h

Location: Room A704

Get together: Before the talks, 14:55 h

28 November 2017

 

Chemical Biology Tools to Perceive and Perturb Glycans and Carbohydrate Processing Enzymes in Living Systems

Prof. Dr. David Vocadlo, Simon Fraser University

12 December 2017

 

A Ring to Rule Them All: From Cell Polarity to Bacterial Virulence Control

Prof. Dr. Urs Jenal, Biozentrum Basel

09 January 2018

 

Unraveling Biomolecular Recognition and Dynamics in Solution using NMR-Spectroscopy and Integrative Structural Biology

Prof. Dr. Michael Sattler, TU München

16 January 2018

 

A Ribozyme With Multiple Functions – Molecular Gymnastics of a Small RNA

Prof. Dr. Sabine Müller, University of Greifswald

Summer term 2017

Time: Tuesdays, 15:15 h

Location: Room A704

Get together: Before the talks, 14:55 h

20 June 2017

 

The Role of the Two Helicases XPD and RecQ4 in Genome Maintenance

Prof. Caroline Kisker, University of Würzburg

27 June 2017

 

SUMO Rules

Dr. Andrea Pichler, MPI Freiburg

04 July 2017

 

New Spectroscopic and Thermodynamic Approaches for The Characterization of Macromolecule-Ligand Interactions

Prof. Dr. Dariush Hinderberger, University of Halle-Wittenberg

18 July 2017

 

Conformational Control of Bacterial Clp Protease by Acyldepsipeptide Antibiotics

Prof. Dr. Heike Brötz-Oesterhelt, University of Tübingen

Winter term 2016/2017

Time: Tuesdays, 15:15 h

Location: Room A704

Get together: Before the talks, 14:55 h

15 November 2016

 

How Pathogenic Bacteria Subvert Host Ubiquitin Signaling

Dr. Jonathan Pruneda, MRC Cambridge

06 December 2016

 

Understanding Biological Nitrogen Fixation

Prof. Dr. Oliver Einsle, University of Freiburg

24 January 2017

 

The Cyanobacterial Toxin Microcystin Interferes With Major Path of Carbon in Bloom-Forming Cyanobacteria

Prof. Dr. Elke Dittmann, University of Potsdam

07 February 2017

 

Cellular Factors Implicated in Amyloid Fibril Homeostasis

Prof. Dr. Michael Ehrmann, University of Duisburg-Essen

Summer term 2016

Time: Tuesdays, 15:15 h

Location: Room A704

Get together: Before the talks, 14:55 h

19 April 2016

 

Peptide-Hypermodifying Enzymes from Microbial Dark Matter

Prof. Dr. Jörn Piel, ETH Zürich

26 April 2016

 

Phage Selection of Bicyclic Peptides for Application as Therapeutics

Prof. Dr. Christian Heinis, EPFL Lausanne

10 May 2016

 

The Busy Life of Nascent Chains: Mechanisms of Folding of Newly Synthesized Proteins

Prof. Dr. Bernd Bukau, ZMBH Heidelberg

07 June 2016

 

Structural Studies of the 26S Proteasome ex situ and in situ

Prof. Dr. Wolfgang Baumeister, MPI Martinsried

Winter term 2015/2016

Time: Tuesdays, 15:15 h

Location: Room A704

Get together: Before the talks, 14:55 h

17 November 2015

 

Trigger Waves in Mitosis and Apoptosis

Prof. Dr. James Ferrell, Stanford University

01 December 2015

 

Phase Separation in Cytoplasm: Implications for Polarity and Neurodegeneration

Prof. Dr. Tony Hyman, MPI Dresden

15 December 2015

 

Prokaryotic Ubiquitin-like Tagging and Other Paths to the Bacterial Proteasome 

Prof. Dr. Eilika Weber-Ban, ETH Zürich

12 January 2016

POSTPONED!

The Busy Life of Nascent Chains: Mechanisms of Folding of Newly Synthesized Proteins

Prof. Dr. Bernd Bukau, ZMBH Heidelberg

Summer term 2015

Time: Tuesdays, 15:15 h

Location: Room A704

Get together: Before the talks, 14:55 h

28 April 2015

 

Direct Cross Talk Between PP1 and PP2A Regulates Mitotic Progression

Prof. Dr. Iain Hagan, University of Manchester

05 May 2015

 

Assembling the Pieces of Protein Puzzles

Prof. Dr. Gerhard Hummer, MPI Frankfurt

23 June 2015

 

Mitotic Wnt Signaling 

Prof. Dr. Christoph Niehrs, IMB Mainz

30 June 2015

 

The Chemical Biology of Lipid Signaling

Dr. Carsten Schultz, EMBL Heidelberg

Winter term 2014/2015

Time: Tuesdays, 15:15 h

Location: Room A704

Get together: Before the talks, 14:55 h

18 November 2014

 

Cytotoxic Peptide-Drug Conjugates Based on Cryptophycins

Prof. Dr. Norbert Sewald, University of Bielefeld

16 December 2014

 

Masters of Reduction: Control of Chromosome Segregation in Meiosis

Dr. Wolfgang Zachariae, MPI Martinsried

27 January 2015

 

Synthetic DNA and RNA Architectures: Fluorescence, Photochemistry and Imaging

Prof. Dr. Hans-Achim Wagenknecht, KIT Karlsruhe

03 February 2015

 

Cellular Protein Quality Control Pathways: Mechanisms and Unexpected Findings

Prof. Dr. Dieter Wolf, University of Stuttgart

Summer term 2014

Time: Tuesdays, 15:15 h

Location: Room A704

Get together: Before the talks, 14:55 h

13 May 2014

 

Mechanism and Regulation of Macromolecular Transport across the Nuclear Envelope

Prof. Dr. Karsten Weis, ETH Zürich

03 June2014

 

Chemical Oncology – Converging Chemical Biology, Cancer Genetics and Medicinal Chemistry

Prof. Dr. Daniel Rauh, TU Dortmund

17 June 2014

 

Chemical Biology of AdoMet-dependent Methyltransferases: Synthetic Cofactor Analogues for Affinity-based Protein Profiling and Substrate Labeling

Prof. Dr. Elmar Weinhold, RWTH Aachen

01 July 2014

 

Expanding the Epigenetic DNA Alphabet

Prof. Dr. Thomas Carell, LMU München

Winter term 2013/2014

Time: Tuesdays, 15:15 h

Location: Room A704

Get together: Before the talks, 14:55 h

26 November 2013

 

How Separase, Cohesin & Shugoshin Choreograph the Chromosomal-Ballet of Mitosis

Prof. Dr. Olaf Stemmann, University of Bayreuth

17 December 2013

 

Cyclic-di-GMP Signaling and Bacterial Biofilm Formation

Prof. Dr. Regine Hengge, Humboldt University Berlin

28 January 2014

 

Translating DRiPs for Immunosurveillance

Prof. Dr. Jonathan Yewdell, NIH, Bethesda, USA

11 February 2014

 

Cellular Mechanisms of Neurodegeneration

Prof. Dr. Christian Haass, University of Munich

Summer term 2013

Time: Tuesdays, 15:15 h

Location: Room A704

Get together: Before the talks, 14:55 h

28 May 2013

 

The Molecular Basis of the von Hippel Lindau Cancer Syndrome

Prof. Dr. Wilhelm Krek, ETH Zürich, Switzerland

04 June 2013

 

2 inactive 4 destruction or the tails of p63

Prof. Dr. Volker Dötsch, University of Frankfurt

02 July 2013

 

Heat Shock Proteins and Protein Aggregation Diseases

Prof. Dr. Harm Kampinga, University of Groningen, The Netherlands

01 August 2013

(Thursday)

Adapting the Chemistry and Biology of Proteostasis to Ameliorate Disease

Prof. Dr. Jeff Kelly, SCRIPPS Research Institute, USA

Winter term 2012/2013

Time: Tuesdays, 15:15 h

Location: Room A704

Get together: Before the talks, 14:55 h

27 November 2012

 

Signalling and Mechanics at the Human Mitotic Centromere and Kinetochore

Prof. Dr. Jason Swedlow, University of Dundee, UK

18 December 2012

 

Prolyl Isomerization in Protein Folding and Protein Function

Prof. Dr. Franz-Xaver Schmid, University of Bayreuth

15 January 2013

 

From Single Molecules to Cellular Function – Protein Translocation into Chloroplasts

Prof. Dr. Enrico Schleiff, University of Frankfurt

19 February 2013

 

Chemical Tools in Chromatin Research

Prof. Dr. Dirk Schwarzer, University of Tübingen

Summer term 2012

Time: Tuesdays, 17:00 h

Location: Room A703

Get together: Before the talks, 16:40 h

Regulating Nuclease Activity in human DNA Repair Pathways

Prof. Dr. Orlando Schärer, Stony Brook, NY, USA

19 June 2012

 

Proteostasis of Rubisco: Folding, Assembly and Activation Mediated by Chaperones

Dr. Manajit Hayer-Hartl, MPI of Biochemistry, Martinsried

26 June 2012

 

Transport and Assembly of Mitochondrial Proteins

Prof. Dr. Nikolaus Pfanner, University of Freiburg

17 July 2012

 

Transmembrane Signaling and Transport: Membrane Protein Dynamics Studied by Site-Directed Spin Labeling EPR

Prof. Dr. Heinz-Jürgen Steinhoff, University of Osnabrück